CAS InsightsTM
Accelerating your scientific progress by revealing unique connections and perspective at the intersection of science, technology, and innovation.
Predicting and countering chemical threats: The strategic role of data-driven technologies
Data-driven technologies play a pivotal role in swift analysis and quick response to chemical threats. Optimize threat assessment and risk management strategies with quality digital solutions.
Science Fact Fiction: Can we really recycle semiconductors?
Untangling the truth about semiconductor recycling: explore the challenges & opportunities of recycling semiconductors from designs, builds, and the future.
Idea in brief: battling antibiotic resistant infections
Discover the research landscape in the fight against antimicrobial resistance and see. the trends, challenges, and AI's promising role.
Keeping a finger on the pulse of exosome IP and innovation
This executive summary highlights why exosomes are becoming popular in many industries. See the importance of protecting exosome IP for your next innovation.
Infographic: Sustainable crops start with green(er) fertilizers
A visual infographic shows how new innovations like biorefineries, waste repurposing, and materials are reshaping the future of sustainable fertilizers.
Webinar: Scientific breakthroughs and emerging trends to watch in 2024
Stay ahead of the curve with insights from experts! Join our webinar featuring Lawrence Livermore National Lab, Oak Ridge National Lab, The Ohio State University, and CAS. Discover trends like AI’s impact in R&D, biomaterials, and tackling the undruggable.
How biomarkers unlock faster cancer detection, improving outcomes
Learn how biomarkers can improve cancer detection and treatment outcomes, and discover the latest research on pancreatic and liver cancer biomarkers. Read more.
Biomarkers: The key to earlier cancer detection and patient outcomes
Learn how cancer biomarkers can help detect and treat cancer early. Read this report by CAS and Excelra to discover the latest advances and trends.
R&D Insight: Unique views into immuno-oncology
This shareable executive summary identifies emerging trends in the rapidly changing immuno-oncology field. This highlights key players, new connections, and emerging opportunities ahead.
AI’s emerging role in natural product drug discovery
AI re-defines natural product drug discovery. See how machine learning unlocks diverse drug candidates from plants, microbes & more, accelerating discovery
Bacteria vs. science: A race against the resistance
Antimicrobial-resistant infections are a global public health crisis. In a race against drug-resistant bacteria, new solutions like AI, alternative therapeutics, and innovations in materials.
Reducing waste through digital transformation
Learn how digital transformation is reducing waste and creating new revenue streams for companies as they repurpose waste byproducts.
Emerging trends in immunotherapy and cancer
Uncover the emerging trends in immune-oncology publications and research areas in this article that identifies new opportunities and challenges ahead.
Dealing with the challenges of drug discovery
Learn more about how the pharma industry is tackling the challenges of drug discovery such as rising costs, and poorly understood disease mechanisms.
Making pharmaceutical formulation data discoverable
Pharmaceutical manufacturers are investigating ways to cultivate insights from dark formulations data, turning once-hidden knowledge into drug discoveries.
Four uses for renewable feedstock in sustainable coatings
With the push towards increased sustainability, here are 4 ways coatings manufacturers are making use of renewable feedstock for their own products.
Can pharma overcome obesity?
Discover how Ozempic, Wegovy, and Mounjaro are part of a new class of semaglutides (GLP-1 receptor agonists) that help treat obesity and diabetes by regulating blood sugar and appetite.
Are covalent inhibitors the key to curing cancer?
Discover how targeted covalent inhibitors are revolutionizing cancer treatments by activating previously undruggable targets, such as RAS genes and PI3Kα. This expert webinar with Totus Medicines and CAS shows the latest trends and insights on covalent inhibitors.
Tiny technology, big possibilities
Discover the emerging landscape of single walled carbon nanotubes, the new applications and approaches across industries, and what future opportunities they offer.
Challenges and opportunities in protein function prediction for drug discovery
In this article, we speak with Iddo Friedberg, an expert in protein function prediction, about how well current prediction models are performing and more.
R&D insights: The covalent inhibitor revolution
See how covalent inhibitors with drugs like ibrutinib and afatinib are changing cancer therapies. Identify emerging opportunities in this sharable summary.
The rise of covalent inhibitors in strategic therapeutic design
Learn how covalent inhibitors are revolutionizing therapeutic design with their unique mechanism of action, advantages, and challenges.
R&D insights: Antibody-drug conjugates
See how antibody drugs are changing cancer therapies and identify emerging opportunities in this sharable research summary.
Unveiling the potential of the antibody drug conjugate
Learn how antibody-drug conjugates (ADCs) are transforming cancer treatment with their targeted and potent action. Discover the latest trends and developments in ADC research and development.
Quantum dots win the 2023 Nobel Prize for Chemistry
Just in time for #Nobel season, discover the most overlooked ideas that have yet to win a Nobel Prize. From OLEDs to MOFs to mRNA therapeutics and more, these ideas have reshaped science and technology. Join the conversation on LinkedIn.
Prior art search and analysis for scientific IP strategies
Incomplete prior art searches and analyses can lead to costly mistakes, leaving innovations and the value of intellectual property open to huge risk. Learn more here.
Digital transformation in the chemical industry: Steps to a sustainable future
Learn how digital initiatives are transforming the chemical industry, allowing for faster innovation and a sustainable future.
Navigating patentability assessments in scientific industries
Learn about the unique challenges of patentability assessments within scientific industries and best practices to help address those challenges.
Webinar on gut microbiome-brain alliance: The connection to health and disorders
Explore the fascinating connection between the gut microbiome and the brain in this webinar featuring experts from CAS, Bayer, and Caltech. Learn how the gut-brain axis influences health from IBS to autism and how microbiome manipulation can offer new therapeutic strategies.
Pharma data management: Revealing breakthroughs that lie in darkness
Strategies to unlock dark data in the pharmaceutical industry. Reveal data insights and accelerate innovation through digitization and knowledge management.
CAS Symposium Explores Convergence of Biology and Chemistry in Emerging Therapeutics
Discover how experts from CAS, LaJolla Institute for Immunology, and Avidity Biosciences are exploring the convergence of biology and chemistry in emerging therapeutics for cancer, vaccines, and more. The recap and slides are here.
Digital transformation in pharma: Improving R&D through digital solutions
Learn how digital initiatives are transforming the pharmaceutical industry, allowing for faster drug development and expanded treatment options.
Understanding the power of catalysis
Discover how catalysts and catalysis have transformed our world, from ancient times to modern sustainability. Learn about the latest research trends and innovations in this fascinating field of chemistry.
Going green with plant-based meat sustainability
With consumers changing their diets for personal and health reasons, innovation to increase quality and variety creates a diverse and competitive market.
Multifunctional cosmetics: Developing a product that ‘does it all’
Learn how hero ingredients can help create more advanced and versatile formulations than ever before as consumers slim down their cosmetic routines.
Mars is calling, but how will Artemis fuel the journey?
Learn how chemistry powers space exploration with rocket fuel and engine technologies. Discover the advantages and challenges of using LOX/LH2 as a propellant for the Artemis mission.
R&D insights: Sustainable catalysts for the future
Learn how catalysts have been shaping human history and enabling sustainable chemistry in this executive summary. Discover current research trends and future opportunities in using non-noble metals as catalysts.
Are large language models right for scientific research
ChatGPT has redefined the conversation around AI but is it right for scientific research? Find out more about the path ahead for LLMs in science.
From fighting viruses to tackling tumors: Harnessing mRNA vaccines to treat cancer
Learn how mRNA vaccines, which have revolutionized the fight against COVID-19, can also be used to treat cancer by harnessing the power of the immune system.
Top 10 emerging trends in biomaterials
Biomaterials are re-shaping the landscape of drug delivery, diagnosis, and therapeutics, learn more about the top ten emerging trends in this space. Key materials covered include hydrogels, lipid nanoparticles, exosomes, bioinks, programmable biomaterials, and more.
Patent searching: Going beyond the basics to increase efficiency
Learn how leveraging tools and strategies can accelerate your path toward comprehensive searches and better patent insights.
Aging reimagined: Exploring the potential of anti-aging treatment strategies
Discover the latest in anti-aging treatment strategies to promote health and longevity. Uncover the latest research on stem cell therapies, hyaluronic acid, senolytics, gene therapy, and a pipeline analysis of ongoing clinical trials in our latest article.
Executive summary: What’s next in anti-aging treatments?
This one-page executive summary on anti-aging strategies and treatments highlights emerging trends, new approaches, and future opportunities from stem cell therapies, prescription drugs, and lifestyle changes. This includes key take-aways of clinical trial pipeline analysis and a landscape view of emerging treatment strategies.
The why’s and how’s of partnerships in scientific patent searching
Accelerate and improve the ROI of your IP and R&D initiatives by partnering with an industry and IP expert. Learn more on how CAS can help.
Infographic: What can be done about microplastics?
Discover how microplastics have infiltrated our entire world and the innovative new approaches that are being used to remove them in our latest infographic.
Challenges and opportunities in sequence analysis during drug discovery
In this Challenges and Opportunities article, we talk with Jefferson Parker, an expert in data analytics for life sciences, about sequence analysis for drug discovery and the frontiers for AI in computational biology.
Supercapacitor technologies: Is graphene finally living up to its full potential?
Supercapacitors vs. batteries: Is graphene the key to unlocking their full potential? Learn how graphene-based supercapacitor technologies are ready for real-world applications and what challenges they face.
Targeted protein degradation and induced proximity: Molecular glues landscape in drug discovery
Induced-proximity target protein degradation (TPD) is a ground-breaking strategy in drug discovery that has emerged in the last decade. This CAS white paper surveys the research landscape, status of clinical trials, and discusses possible future opportunities.
Maximize opportunities with a patent landscape analysis
Learn how a successful patent landscape analysis can maximize opportunities and de-risk your company's R&D program and other initiatives.
Top emerging trends in mRNA therapeutics: Executive summary
This idea in brief provides an overview of the latest trends and emerging opportunities in mRNA research and development. It discusses the key benefits of mRNA technologies, the challenges that remain, the key players, and their areas of focus.
Unlocking the power of dark data in chemistry R&D: Strategies for success
Strategies to unlock dark data in Chemistry R&D. Reveal data insights and accelerate innovation through knowledge management and data strategy planning.
Infographic: 3D printing, re-shaping the future of biomedicine
See how 3D printing is finally transforming biomedical applications in our new infographic. See how advances in materials and approaches have re-shaped the following areas: sourcing of tissues, transplants, and organs, new drug delivery methods, and advances in surgical settings and wound care.
Webinar on 3D printing in biomedicine: CAS, Harvard, Carnegie Mellon, and the University of Toronto
Discover how exosomes, nature's lipid nanoparticles, are reshaping drug delivery and treatment of diseases from cancer to cardiovascular disease and beyond. Learn from experts at Mayo Clinic, Direct Biologics, and Aruna Bio in our recent ACS webinar. Watch the recording and read the full Insight Report now.
Infographic: Top investment trends for RNA and the outlook ahead
Discover how RNA therapeutics are transforming medicine in our new infographic. Learn about the applications, challenges, and opportunities of this cutting-edge technology in cancer, infectious diseases, liver, and metabolic diseases. Find out the latest trends and data on key nanoparticles, emerging types of RNA, and modified sequences in this rapidly evolving space.
Five ways to achieve sustainable medical packaging
Learn five ways to reduce waste and use biodegradable materials to develop sustainable sterile packaging options for medical devices.
The Ultimate Guide for PEGylated Lipid Nanoparticles
Learn how to overcome PEG immunogenicity, a challenge that affects the safety and efficacy of PEGylated lipid nanoparticles for drug delivery. This article reviews the current state-of-the-art in addressing PEG immunogenicity, from elucidating the factors that influence anti-PEG antibody production to developing novel drug vehicles or optimizing administration and posology.
Peer-reviewed journal: PEG immunogenicity and vaccine safety
This peer-reviewed journal publication in Bioconjugate Chemistry shows how PEGylated lipid nanoparticles are used to deliver mRNA vaccines and other drugs, the immunogenicity concerns with vaccines, and emerging approaches on new designs to increase efficacy and safety.
Exec Summary: What you need to know about PEG immunogenicity
Learn how to address PEG immunogenicity, a challenge that affects the safety and efficacy of PEGylated lipid nanoparticles for drug delivery. Discover the latest R&D trends, market data, and opportunities in this cutting-edge field including COVID-19 vaccines and a wide range of current and future drugs that leverage these nanoparticles.
Peer-reviewed journal: PEG immunogenicity and vaccine safety
This peer-reviewed journal publication in Bioconjugate Chemistry shows how PEGylated lipid nanoparticles are used to deliver mRNA vaccines and other drugs, the immunogenicity concerns with vaccines, and emerging approaches on new designs to increase efficacy and safety.
Challenges and opportunities in structure-activity-relationship (SAR) studies
In this edition of the CAS article series, Challenges & Opportunities in Drug Discovery, we talk with Ben Taft, the Senior Director of Chemistry at Via Nova Therapeutics, about structure-activity relationship studies and the possible frontiers for bioactivity data.
Friend, not foe: Harnessing the gut microbiome for health benefits
The gut microbiome is a complex ecosystem of trillions of bacteria that live in our digestive tracts with health benefits like immunity, improved mental health, and therapeutic options. In recent years, there has been a growing interest in the potential of microbiome therapies to treat a variety of diseases. As our understanding of the gut microbiome continues to grow, we can expect to see more advances in microbiome therapies in the years to come.
Recognizing the potential of the gut microbiome
This report features a comprehensive landscape analysis of the gut microbiome, including its composition, functions, and role in health and disease. Created in collaboration with Bayer AG, this article discusses the latest research on microbiome-based therapies, microbiota, probiotics, and the wide range of health conditions it can influence, like obesity, diabetes, inflammatory bowel disease, and even mental health disorders.
Peer reviewed publication: New discoveries on emerging microbiome trends
This peer-reviewed publication in the ACS Chemical Neuroscience Journal details a landscape analysis of emerging trends in the gut microbiome space. It dives deep into an overview of microbiome therapies, emerging approaches, new science, clinical pipelines, and key players in this space.
R&D Insights: Tiny microplastics with massive implications
Microplastic pollution is a global problem and can be ingested by animals and humans. They can also accumulate in soil and water, where they can disrupt ecosystems. There is a growing body of evidence that suggests that microplastics can be harmful to health. This executive summary highlights key sources of microplastic pollution, health risks, and steps that can be taken to reduce microplastic pollution
Advancing progress in the fight against fentanyl
As the leading cause of drug-related deaths, fentanyl has become a public health crisis, but new breakthroughs in developing safer pain medications, reducing side effects, and developing a vaccine may reduce future deaths.
Exosomes, the rising star of therapeutics: Infographic
Exosomes are reshaping the future of drug delivery, therapeutics and diagnostics in cancers and beyond. This full-sized infographic details critical types of exosomes, the diseases (like cancer) being studied, and a deeper dive into the challenges that need to be addressed before its robust clinical pipeline is approved.
R&D Insights: 3D printing in biomedical applications
Understand emerging trends of 3D printing in biomedical applications and the new technologies that are reshaping personalized healthcare. From 3D printing devices to custom drug delivery and printing bioactive tissues and organs, this field is innovating rapidly with implications across the healthcare industry.
Top emerging trends in synthetic organic chemistry
Detailed landscape report on top emerging trends in synthetic organic chemistry.
Synthetic organic chemistry: peer-reviewed landscape publication
Peer reviewed journal article published in collaboration with the National Natural Science Foundation of China and National Science Library at the Chinese Academy of Sciences and CAS, a division of the American Chemical Society in the Journal of Organic Chemistry and Organic Letters on the state of global synthetic organic chemistry research with a focus on enzyme catalysis, photocatalysis, and green chemistry.
R&D Insights: sustainable agriculture and fertilizer production
For the executive who needs to quickly understand emerging trends around sustainable agriculture, green fertilizer production, and reducing the carbon emissions of agriculture this idea in brief will provide unique insights for their R&D teams.
The science behind dioxins, vinyl chloride, and proven remediations
Discover the science behind vinyl chloride, dioxins and different remediations being developed. Explore the latest patent trends, research publications, and data challenges surrounding dioxins and vinyl chloride to understand how we can better manage hazardous material transportation in the future.
Webinar on nature’s lipid nanoparticles: Exosomes
Discover how exosomes, nature's lipid nanoparticles, are reshaping drug delivery and treatment of diseases from cancer to cardiovascular disease and beyond. Learn from experts at Mayo Clinic, Direct Biologics, and Aruna Bio in our recent ACS webinar. Watch the recording and read the full Insight Report now.
RNA medicines: what technologies are investors funding?
Learn about market trends in the RNA medicine space and what technological approaches and indications investors are backing.
R&D Insights: exosomes in drug delivery and diagnostics
For the executive who needs to quickly understand emerging trends around exosomes, lipid nanoparticles, and their impact on drug delivery, diagnostics, and therapeutics this idea in brief will provide unique insights for their R&D teams.
New advances in recycling of lithium-ion batteries
Learn about the latest advancements in lithium-ion battery recycling technology in this article. Discover a new approach for direct recycling that could make it possible to repair and reuse depleted batteries at a lower cost. Understand the challenges still facing the industry and the potential impact on the future of battery recycling.
From polymers to prosthetics: the growth of 3D printing in biomedicine
Explore the limitless potential of 3D printing in biomedicine with this in-depth report. From prosthetic ears to artificial organs, learn about the latest trends and innovations. Discover the potential that 3D printing in biomedicine holds for manufacturing, forensic pathology and more.
Trends and innovations in biomedical 3D printing
Discover the innovative applications of biomedical 3D printing, starting with from a short history of the technology, all the way to the latest trends of 3D printing in healthcare.
Explore biomedicine’s 3D printing scientific journal review
Explore the possibilities of 3D printing in biomedicine with this analysis from a scientific journal. From the production of tissues and organs to personalized prostheses and medications, learn about the challenges overcome and how 3D printing in biomedicine will re-shape the future.
Is nuclear energy critical in solving climate change?
Read more on how nuclear energy could play a part in solving climate change and recent advances in the design of nuclear reactors.
Top scientific breakthroughs and emerging trends for 2023
Stay ahead of the curve with the latest in emerging science and cutting-edge research that is accelerating the landscape of innovation. From new discoveries in synthetic biology to breakthroughs in sustainable energy, these are the breakthroughs that will reshape 2023. The experts at CAS reveal unique analysis and emerging trends from their landscape view of the world’s science.
Innovation in sustainable fertilizer production
Detailed landscape report on the latest trends in sustainable agriculture and fertilizer production, new opportunities and insights on the scientific advancements that will enable future innovation
Scientific review on sustainable fertilizers
Scientific journal review examines and analyzes the scientific and patent publication trends so the scientific community understands key breakthroughs to build upon, emerging compounds, and the challenges ahead.
Hydrogen fuel-Insights into a growing market
Download this in-depth CAS Market Report to gain insight into the evolution of hydrogen fuel technology, the global innovation landscape, key market trends and potential applications and opportunities.
Reduce, reuse, recycle: the path to sustainable agriculture
Explore the path to sustainable agriculture and learn about the key role it plays in global food production. Discover how reducing, reusing, and recycling can improve fertilizer access, minimize environmental impact and dependence on finite resources, and lead to a circular bioeconomy. Learn about the latest innovations in sustainable agriculture, including smart nano-fertilizers, biorefineries, and biochar, and see how they can be used to harness the nutrient content of waste products to bolster food production and protect the environment.
Microplastics: tackling the invisible enemy
In-depth, detailed landscape report that reveals new approaches, publication trends, and ideas gaining traction in the fight against microplastics pollution.
Scientific review on microplastics pollution
Scientific journal review detailing the emerging landscape of microplastics research, publication, and patent trends. This analysis highlights new opportunities and challenges facing humanity that is awash in microplastics.
Are we doing enough to solve the major issue of microplastics?
Understand the environmental threat of microplastics by exploring its impact through resources such as the 2022 WHO report on dietary and inhalation exposure to microplastics, and microplastics publications trends.
ACE2: Targeting a potentially important receptor in disease pathogenesis
Learn more about ACE2 the critical protein that remains the critical target of COVID-19 and so many additional viral infections. This overviews emerging trends and insights on publications, milestones, and future applications to target ACE2 proteins.
Exosome research: from platelet dust to pioneering therapeutics
Landscape view of emerging contributors, companies, and researchers in the emerging field of exosome research. This article overviews key players in diagnostics and therapeutic fields of exosome research with a deeper look into the current clinical pipeline.
Expedited FDA designation of breakthrough therapy
The FDA can designate drug candidates as “breakthrough therapies” (breakthrough therapy designation or BTD) for certain drug candidates that demonstrate substantial improvement over available therapies on a clinically significant endpoint. This infographic highlights the value of this designation, key requirements, and factors that go into this designation.
Exosome therapy and diagnostics: the path to becoming clinical giants
Exosomes’ unique physical properties could unlock massive changes in the fields of drug delivery and diagnostics. However, the biggest challenge for exosomes is the methodologies of isolation and purification – this article discusses the recent trends and applications of exosomes in drug delivery, diagnostics, and therapeutics.
The evolving exosome: from small player to rising star
A historical overview of the discovery of exosomes, key milestones in their rise, and why they will revolutionize the diagnostic and drug delivery fields in the future.
Exosomes: Reshaping drug delivery and diagnostics
Exosomes are nature’s lipid nanoparticles and their unique physical properties will unlock new applications in drug development, delivery and diagnostic applications in the future
Exosomes – nature's lipid nanoparticle, a rising star in drug delivery and diagnostics
Exosomes – nature's lipid nanoparticle, a rising star in drug delivery and diagnostics
Bioorthogonal chemistry and its applications
Bioorthogonal chemistry is a set of methods that use the chemistry of non-native functional groups to analyze biology in living organisms.
Ammonium nitrate: making it safer today for a better tomorrow
Ammonium nitrate has the power to feed billions, yet when stored improperly is like a bomb waiting to happen. How can we make this fertilizer safer? Learn about emerging science, safer alternatives, and best practices for safe storage and transport.
The therapeutic potential of nanotechnology beyond COVID-19
Learn more about lipid nanoparticles, their origin, role in COVID vaccines, and future applications. This overviews emerging trends and insights on publications, milestones, and future applications in vaccines, drug delivery, and non-therapeutic applications like agro-chemistry, cosmetics, and food science.
Cytokine storm warning: The critical role of cytokines in immunity and infection
Learn more about cytokine storms and their role in both immunity and severe infection with COVID-19 and additional viral infections. This overviews emerging trends and insights on publications, milestones, and future applications to minimize the impact of cytokine adverse effects.
Hidden greenhouse gas emissions in plant growth
Learn more about the hidden greenhouse gas emissions of plants, a more sustainable approach to fertilizer production, and new approaches to make phosphorus more recyclable.
Predictive chemical deformulation flips the formulation challenge
Deformulation is the process of reverse-engineering the composition of known formulations. This publication shows the value of consistent and highly structured representations in predictive models.