Learn how to overcome PEG immunogenicity, a challenge that affects the safety and efficacy of PEGylated lipid nanoparticles for drug delivery. This article reviews the current state-of-the-art in...
The gut microbiome is a complex ecosystem of trillions of bacteria that live in our digestive tracts with health benefits like immunity, improved mental health, and therapeutic options. In recent...
As the leading cause of drug-related deaths, fentanyl has become a public health crisis, but new breakthroughs in developing safer pain medications, reducing side effects, and developing a vaccine may...
Stay ahead of the curve with the latest in emerging science and cutting-edge research that is accelerating the landscape of innovation. From new discoveries in synthetic biology to breakthroughs in...
Learn about the basics of click chemistry and bioorthogonal chemistry that was recently awarded the 2022 Nobel Prize in Chemistry. Read about emerging trends, insights on publication trends, and...
NASA’s Artemis Program has also focused attention on topics such as food safety, reliability, and nutrition in space. This blog touches on novel approaches to these problems like 3D printed space...
With recent headlines on monkeypox, learn more about the research landscape, scientific profiles, and currently available therapies. A deeper understanding of the published science enables clarity...
Gut microbiota, gut flora, or microbiome are the microorganisms that live in the digestive tracts of humans and other animals. While some bacteria are associated with disease, others are particularly...
Recent clinical trials show that psychedelics like LSD, MDMA, and Psilocybin - when properly controlled for dosing and administration - are having positive outcomes in treating mental health...
COVID-19 vaccine production is limited by the output of lipid nanoparticles, but use of microfluidic technology has been successful in producing lipid nanoparticles.
Performance enhancing drugs are constantly scrutinized, tracked, and tested for by the International Olympic Committee, US Anti-Doping Agency and World Anti-Doping Agency. This blog will provide...
Learn about the latest advancements in lithium-ion battery recycling technology in this article. Discover a new approach for direct recycling that could make it possible to repair and reuse depleted...
Discover the innovative applications of biomedical 3D printing, starting with from a short history of the technology, all the way to the latest trends of 3D printing in healthcare.
Understand the environmental threat of microplastics by exploring its impact through resources such as the 2022 WHO report on dietary and inhalation exposure to microplastics, and microplastics...
Learn more about lipid nanoparticles, their origin, role in COVID vaccines, and future applications. This overviews emerging trends and insights on publications, milestones, and future applications in...
This blog details the recently published CAS indicator of drug innovation based on the structural novelty of new molecular entities (NMEs) which may better assess innovativeness of new drugs.
Find out how companies improve their prediction accuracy, obtain Breakthrough Technology Status and shorten the development and review time of new drugs by leveraging CAS advanced machine learning...
It is estimated that one in five human cancers involve RAS mutations. Although once considered undruggable, this blog looks at recent advances in RAS inhibitors and emerging therapies.
The COVID pandemic revealed deficiencies in mask development and production. Innovation will be crucial in slowing the spread of new variants of the virus. There are many factors that can be improved...
As COVID-19 cases rise again worldwide, the Omicron subvariant BA.5 is currently the dominant strain. This blog explores some key mutations that increase transmission, evade protective antibodies, and...
Molecular glues have been used to uncover new therapeutic agents. Because of their targeted protein degradation that holds them together, these glues have exciting potential in uncovering new drugs to...
We are in the midst of a therapeutic revolution, according to the authors of a recent review article in Frontiers in Bioengineering and Biotechnology. They were commenting on the rapid expansion of...
A literature search in the CAS Content Collection provides useful insights into recent and ongoing intensive research and development into green hydrogen production, storage, and utilization in fuel...
This blog is focused on lesser-known cannabinoids, their key medicinal benefits discussed in the scientific literature, and a deeper view into their chemical structures.
Bioorthogonal chemistry has a wide range of applications in science and medicine, and has been used to progress research significantly in recent years. In addition to propelling the field of...
Preliminary study of the Omicron variant indicates that it has evolved significantly from the original version of the virus first identified in China in 2019, which means there is an increased...
In support of ongoing research efforts to identify additional drugs for COVID-19, a team of CAS scientists analyzed published scientific information and created a comprehensive report focusing on...
